Publications
Influenza
Karch CP, Li J, Kulangara C, Paulillo SM, Raman SK, Emadi S, Tan A, Helal ZH, Fan Q, Khan MI, Burkhard P (2017). Vaccination with Self-Adjuvanted Protein Nanoparticles Provides Protection against Lethal Influenza Challenge. Nanomedicine, doi: 10.1016/j.nano.2016.08.030.
Burkhard P, Karch CP (2017). Self-assembling protein nanoparticles: a promising tool against lethal influenza?Nanomedicine (Lond). 12(13):1529-1531. doi: 10.2217/nnm-2017-0148.
Babapoor S, Neef T, Mittelholzer C, Girshick T, Garmendia AE, Shang H, Khan MI and Burkhard P. (2011). A novel vaccine using nanoparticle platform to present immunogenic M2e against avian influenza Infection; Influenza Research and Treatment. 2011, Article ID 126794. doi:10.1155/2011/126794
COVID-19
Pimentel T, Yan Z, Hodges RS, Burkhard P. (2009). Peptide nanoparticles as novel immunogens: Design and analysis of a prototype SARS vaccine. Chemical Biology and Drug Design, 73(1):53-61
SAPNs - Design
Indelicato G, Wahome N, Ringler P, Müller SA, Nieh M, , Twarock R (2016). Principles Governing the Self-Assembly of Coiled-Coil Protein Nanoparticles. (3):646-60. doi: 10.1016/j.bpj.2015.10.057.
Raman, S.K., Machaidze, G., Lustig, A., Aebi, U. and Burkhard, P. (2006). Structure-based design of peptides that self-assemble into regular polyhedral nanoparticles. Nanomedicine, 2 (2), 95-102
SAPNs - Immunology
El-Bissati K, Zhou Y, Paulillo SM, Raman SK, Karch CP, Roberts CW, Lanar DE, Reed S, Fox C, Carter D, Alexander J, Sette A, Sidney J, Lorenzi H, Begeman IJ, Burkhard P, McLeod R (2017). Protein nanovaccine confers robust immunity against Toxoplasma. Nature PJ Vaccines, 2, doi:10.1038/s41541-017-0024-6
Kaba SA, McCoy ME, Doll TA, Brando C, Guo Q, Dasgupta D, Yang Y, Mittelholzer C, Spaccapelo R, Crisanti A, Burkhard P, Lanar DE (2012). Protective Antibody and CD8(+) T-Cell Responses to the Plasmodium falciparum Circumsporozoite Protein Induced by a Nanoparticle Vaccine. PLoS One. 7(10):e48304. doi: 10.1371/journal.pone.0048304.